Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1367160 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
Compounds 10a–10d and 10i are very potent inhibitors of Eimeria tenella cGMP-dependent protein kinase (0.081–0.32 nM) and are very efficacious antiparasitic agents in vivo when administered to chickens at 12.5–25 ppm levels in the feed.
Graphical abstractThe imidazopyridine derivatives are discovered as potent inhibitors of the Eimeria tenella cGMP-dependent protein kinase.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Dennis Feng, Michael Fisher, Gui-Bai Liang, Xiaoxia Qian, Chris Brown, Anne Gurnett, Penny Sue Leavitt, Paul A. Liberator, John Mathew, Andrew Misura, Samantha Samaras, Tamas Tamas, Dennis M. Schmatz, Matthew Wyvratt, Tesfaye Biftu,