| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1367357 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
A novel conjugate of 3-Clip-Phen and polyamide containing three N-methylimidazole (Im) rings was synthesized for the targeting human telomeric repeat of 5′-TTAGGG-3′, and the DNA cleaving activity and the sequence selectivity of the complex of copper-conjugate were confirmed by electrospray ionization mass spectrometry.
Graphical abstractA novel conjugate of 3-Clip-Phen and polyamide was synthesized for the targeting human telomeric repeat of 5′-TTAGGG-3′, and the DNA cleaving activity and the sequence selectivity of this complex were confirmed by ESI-mass spectrometry.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Dan Liu, Jiang Zhou, Huihui Li, Bo Zheng, Gu Yuan,