Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1367374 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
We developed novel amino-modifying reagents, of which an amino group was connected with an aromatic residue by aliphatic linker. It was proved that the insertion of the aromatic residue could increase the reactivity of the amino group on oligonucleotides in comparison with conventional amino-modification.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Naoshi Kojima, Maiko Sugino, Akiko Mikami, Ken Nonaka, Yumi Fujinawa, Isamu Muto, Kenichi Matsubara, Eiko Ohtsuka, Yasuo Komatsu,