| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1367463 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
A series of α-amino acids were identified as ligands which compete with gabapentin for binding to the α2δ subunit of voltage-dependent Ca2+ channels. Potent analogs were identified. Their activity in an in vivo pain assay is described.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kathleen H. Mortell, David J. Anderson, James J. Lynch III, Sherry L. Nelson, Kathy Sarris, Heath McDonald, Reza Sabet, Scott Baker, Prisca Honore, Chih-Hung Lee, Michael F. Jarvis, Murali Gopalakrishnan,