| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1367479 | Bioorganic & Medicinal Chemistry Letters | 2006 | 5 Pages |
Abstract
A novel benzimidazole series of small-molecule thrombopoietin receptor agonists has been discovered. Herein, we discuss the preliminary exploration of structure–activity relationships within this chemotype.
Graphical abstractThe synthesis and SAR of a novel, rationally designed series of benzimidazole TPO receptor agonists are reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Igor G. Safonov, Dirk A. Heerding, Richard M. Keenan, Alan T. Price, Connie L. Erickson-Miller, Christopher B. Hopson, Jenna L. Levin, Kenneth A. Lord, Peter M. Tapley,