| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1367515 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
Various berberine derivatives (2–17) were synthesized and their antihyperglycemic activities were evaluated in a model of β-cell-membrane chromatography and a model of alloxan-induced diabetes mice. The results indicated that compounds 5 and 14 exhibited antihyperglycemic activity. Their structure–activity relationships were discussed.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xiaoli Bian, Langchong He, Guangde Yang,