| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1367649 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
Tramadol is a centrally acting opioid analgesic structurally related to codeine and morphine. Analogs of tramadol with deuterium-for-hydrogen replacement at metabolically active sites were prepared and evaluated in vitro and in vivo.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Liming Shao, Craig Abolin, Michael C. Hewitt, Patrick Koch, Mark Varney,