Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1367655 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
Nicotinamide (2) is a potent and selective inhibitor of the PDE4D isozyme and as a chemical tool selectively blocks eosinophil mediator release and chemotaxis thus linking the role of PDE4D to eosinophil function.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Robert J. Chambers, Kristin Abrams, Tessa A. Castleberry, John B. Cheng, Douglas A. Fisher, Ajith V. Kamath, Anthony Marfat, David O. Nettleton, Joann D. Pillar, Eben D. Salter, Alissa L. Sheils, John T. Shirley, Claudia R. Turner, John P. Umland,