Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1367709 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
Cinnamides as novel CCR1 antagonist chemotypes are described with high affinity to human and rodent receptors. A1B1 and A4B7 showed oral activity in the mouse collagen induced arthritis.
Graphical abstractA1B1 and A4B7 showed oral activity in the mouse collagen induced arththritis.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Laszlo Revesz, Birgit Bollbuck, Thomas Buhl, Joerg Eder, Ronald Esser, Roland Feifel, Richard Heng, Peter Hiestand, Benedicte Jachez-Demange, Pius Loetscher, Helmut Sparrer, Achim Schlapbach, Rudolf Waelchli,