| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1367713 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
Starting from 10-deacetylbaccatin III, the 2-debenzoyl-2-m-methoxybenzoyl analogs of the newer generation taxoids IDN5109 and IDN5390 were synthesized. The biological evaluation of these compounds (5 and 6, respectively) showed a general increase of cytotoxicity, as observed in first-generation anticancer taxanes.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Luciano Barboni, Roberto Ballini, Guido Giarlo, Giovanni Appendino, Gabriele Fontana, Ezio Bombardelli,