| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1367728 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
A series of N-[(3S)-1-benzylpyrrolidin-3-yl]-(2-thienyl)benzamides 8 has been prepared and found to bind with high affinity to the human D4 (hD4) and 5-HT2A receptors. Several compounds displayed selectivity for these receptors versus hD2 and α1 adrenergic receptors of over 500-fold.
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Organic Chemistry
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Authors
Jalaj Arora, Michel Bordeleau, Laurence Dube, Keith Jarvie, Lucy Mazzocco, Jack Peragine, Ashok Tehim, Ian Egle,