| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1367741 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
Efforts directed to identifying potent HIV protease inhibitors (PI) have yielded a class of compounds that are not only very active against wild-type (NL4-3) HIV virus but also very potent against a panel of PI-resistant viral isolates. Chemistry and biology are described.
Graphical abstractEfforts directed to identifying potent HIV protease inhibitors (PI) have yielded a class of compounds that are not only very active against wild-type (NL4-3) HIV virus but also very potent against a panel of PI-resistant viral isolates. Chemistry and biology are described.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhijian Lu, Joann Bohn, Tom Rano, Carrie A. Rutkowski, Amy L. Simcoe, David B. Olsen, William A. Schleif, Anthony Carella, Lori Gabryelski, Lixia Jin, Jiunn H. Lin, Emilio Emini, Kevin Chapman, James R. Tata,