| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1367746 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
The synthesis and biological activity of a novel series of 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones are described. Some of these compounds were found to be potent inhibitors of inosine 5′-monophosphate dehydrogenase type II (IMPDH II).
Graphical abstractThe synthesis and biological activity of a novel series of 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones are described. Some of these compounds were found to be potent inhibitors of inosine 5′-monophosphate dehydrogenase type II (IMPDH II).Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Helen L. Birch, George M. Buckley, Natasha Davies, Hazel J. Dyke, Elizabeth J. Frost, Philip J. Gilbert, Duncan R. Hannah, Alan F. Haughan, Michael J. Madigan, Trevor Morgan, William R. Pitt, Andrew J. Ratcliffe, Nicholas C. Ray, Marianna D. Richard,