Article ID Journal Published Year Pages File Type
1367848 Bioorganic & Medicinal Chemistry Letters 2005 5 Pages PDF
Abstract

Modification of the P2 and P1 side chains of earlier P3-capped α-ketoamide inhibitor of HCV NS3 serine protease 1 resulted in the discovery of compound 24 with about 10-fold improvement in potency.

Graphical abstractModification of the P2 and P1 side chains of earlier P3-capped α-ketoamide inhibitor of HCV NS3 serine protease 1 resulted in the discovery of compound 24 with about 10-fold improvement in potency.Figure optionsDownload full-size imageDownload as PowerPoint slide

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Physical Sciences and Engineering Chemistry Organic Chemistry
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