| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1367870 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
We report the solid-phase synthesis and pharmacological evaluation of a new series of small-molecule agonists of the human peroxisome proliferator-activated receptor δ (PPARδ) based on a lead structure from our PPARα program. Compound 33 showed good pharmacokinetics.
Graphical abstractWe report the solid-phase synthesis and pharmacological evaluation of a new series of small-molecule agonists of the human peroxisome proliferator-activated receptor δ (PPARδ) based on a lead structure from our PPARα program. Compound 33 showed good pharmacokinetics.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Stefan Weigand, Hilmar Bischoff, Elke Dittrich-Wengenroth, Heike Heckroth, Dieter Lang, Andrea Vaupel, Michael Woltering,