Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1367958 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
The synthesis of enantiomerically pure (2R,3S)-disubstituted tetrahydropyranes and their in vitro activity against HL60 promyelocytic leukemia cells and MCF7 breast cancer cells are reported. A structure-activity relationship is discussed.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Osvaldo J. Donadel, Tomás MartÃn, VÃctor S. MartÃn, Jesús Villar, José M. Padrón,