Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1367968 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
Novel cyclopentane analogues of fumagillol were synthesized and their endothelial cell proliferation inhibitory activities were evaluated. The cyclopentane-fumagillol derivatives were synthesized from (−)-2,3-O-isopropylidene-d-erythronolactone via stereoselective glycolate Claisen rearrangement and intramolecular ester enolate alkylation as key steps.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Byeong-Seon Jeong, Nam Song Choi, Soon Kil Ahn, Hoon Bae, Hak Sung Kim, Deukjoon Kim,