Article ID Journal Published Year Pages File Type
1367969 Bioorganic & Medicinal Chemistry Letters 2005 4 Pages PDF
Abstract

In a three-step sequence, an array of angularly fused polycyclic heterocycles with coumarin, benzofuran and pyridine rings were synthesized from 4-bromomethylcoumarins and salicylonitrile. All the final compounds were fully characterized and screened for anti-microbial, anti-inflammatory and analgesic activities. Several compounds exhibited promising inflammation inhibiting and anti-microbial properties.

Graphical abstractNovel angularly fused pentacyclic heterocycles with coumarin and benzofuran fused to the pyridine ring were synthesized and show promising anti-inflammatory activities.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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