Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1368504 | Bioorganic & Medicinal Chemistry Letters | 2016 | 4 Pages |
Abstract
We designed and prepared synthetic phospholipids that generate lyso-phosphatidylcholine products with a unique mass for convenient detection by LC–MS in complex biological matrices. We demonstrated that compound 4, formulated either as a Triton X-100 emulsion or incorporated in synthetic HDL particles can serve as a substrate for plasma EL with useful specificity.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Julien P.N. Papillon, Meihui Pan, Margaret E. Brousseau, Mark A. Gilchrist, Changgang Lou, Alok K. Singh, Todd Stawicki, James E. Thompson,