| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1368575 | Bioorganic & Medicinal Chemistry Letters | 2016 | 5 Pages |
Abstract
A series of 2,3-diarylindoles were synthesized via the Larock heteroannulation, and evaluated for their anticancer activity against A549 lung cancer cells. The most potent compound, PCNT13 with IC50 = 5.17 μM, caused the induction of two modes of programmed cell death, apoptosis and autophagy.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Thanya Rukkijakan, Lukana Ngiwsara, Kriengsak Lirdprapamongkol, Jisnuson Svasti, Nared Phetrak, Pitak Chuawong,