| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1368593 | Bioorganic & Medicinal Chemistry Letters | 2016 | 4 Pages |
Abstract
Parallel solid phase synthesis offers a unique opportunity for the synthesis and screening of large numbers of compounds and significantly enhances the prospect of finding new leads. We report the synthesis and antitubercular activity of chiral 1,2,4-trisubstituted piperazines derived from resin bound acylated dipeptides against Mycobacterium tuberculosis strain H37Rv.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kyle H. Rohde, Heather A. Michaels, Adel Nefzi,