| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1368660 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Two DNA minor-groove binding polyamides 1 and 2 were designed and synthesized and evaluated for inhibition of FIV-34TF10 replication. Both 1 and 2 decreased the replicationof FIV-34TF10 by 75% at 0.1 nM concentration by acting at the level of the virus but outside of the LTR or env region.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sanjay K Sharma, Jean-Noel Billaud, Manju Tandon, Olivier Billet, Sam Choi, Mary L Kopka, Tom R Phillips, J.William Lown,