| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1368691 | Bioorganic & Medicinal Chemistry Letters | 2016 | 4 Pages |
Abstract
N1-[1-[1-aryl-3-[4-(1H-imidazol-1-yl)phenyl]-3-oxo]propyl]-pyridine-2-carboxamidrazone derivatives were design, synthesized and tested for their in vitro antimycobacterial activity. The new compounds showed a moderate antimycobacterial activity against the tested strain of Mycobacterium tuberculosis H37Ra and a significant antimycobacterial activity against several mycobacteria other than tuberculosis strains.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Antimycobacterial activity of new N1-[1-[1-aryl-3-[4-(1H-imidazol-1-yl)phenyl]-3-oxo]propyl]-pyridine-2-carboxamidrazone derivatives](/preview/png/1368691.png "First Page Preview: Antimycobacterial activity of new N1-[1-[1-aryl-3-[4-(1H-imidazol-1-yl)phenyl]-3-oxo]propyl]-pyridine-2-carboxamidrazone derivatives")
Authors
Daniele Zampieri, Maria Grazia Mamolo, Luciano Vio, Maurizio Romano, Nataša Skoko, Marco Baralle, Valentina Pau, Alessandro De Logu,