| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1368783 | Bioorganic & Medicinal Chemistry Letters | 2016 | 8 Pages |
Abstract
Chemical modulation of a formerly disclosed DGAT-1 inhibitor resulted in the identification of a compound with a suitable profile for preclinical development. Optimisation of solubility is discussed and a PK/PD study is presented.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Patrick Mougenot, Claudie Namane, Eykmar Fett, Florence Goumy, Rommel Dadji-Faïhun, Gwladys Langot, Catherine Monseau, Bénédicte Onofri, François Pacquet, Cécile Pascal, Olivier Crespin, Majdi Ben-Hassine, Jean-Luc Ragot, Thao Van-Pham,