| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1368845 | Bioorganic & Medicinal Chemistry Letters | 2014 | 5 Pages |
Abstract
A library of diversely stereo-oriented, highly substituted 2,6-cis piperidine derivatives were synthesized, and evaluated for their anticancer activity in cancer cells that included A549 (lung cancer, CCL-185), MCF7 (breast cancer (HTB-22), DU145 (prostate cancer (HTB-81), and HeLa (cervical cancer, CCL-2). One stereo-variant emerged as a promising candidate for further design based structure–activity studies.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gullapalli Kumaraswamy, Rangaraju Satish Kumar, Bitla Sampath, Y. Poornachandra, C. Ganesh Kumar, Sahithya Phani Babu Vemulapalli, Jagadeesh Bharatam,