| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1369047 | Bioorganic & Medicinal Chemistry Letters | 2014 | 4 Pages |
Abstract
A set of vancomycin derivatives with lipid chain attached via a glyceric acid linker was designed and synthesized. A concise synthesis towards these derivatives was developed and the IC50s of these new lipoglycopeptides were tested. Some of them showed very potent activity against both vancomycin sensitive and resistant strains.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Wen Gu, Bei Chen, Min Ge,