Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1369083 | Bioorganic & Medicinal Chemistry Letters | 2015 | 5 Pages |
Abstract
Modulating GPR88 activity is suggested to have therapeutic utility in the treatment of CNS disorders, such as schizophrenia. This Letter will describe the discovery and SAR development of a class of potent GPR88 agonists.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yingzhi Bi, Carolyn D. Dzierba, Cynthia Fink, Yudith Garcia, Michael Green, Jianxin Han, Soojin Kwon, Godwin Kumi, Zhi Liang, Ying Liu, Ying Qiao, Yulian Zhang, Greg Zipp, Neil Burford, Meredith Ferrante, Robert Bertekap, Martin Lewis, Angela Cacace,