| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1369171 | Bioorganic & Medicinal Chemistry Letters | 2013 | 4 Pages |
Abstract
Two new daphnane-type diterpene esters, daphneresiniferins A (1) and B (2), along with seven known diterpenes, yuanhuacine (3), yuanhuadine (4), yuanhuahine (5), genkwadaphnin (6), genkwanine A (7), genkwanine F (8), and genkwanine H (9), were isolated from the methanol extract of the flower buds of Daphne genkwa. Their structures were elucidated on the basis of spectroscopic methods, especially 2D NMR spectra such as HMQC, HMBC, and NOESY. All the isolates were evaluated for their inhibitory effects of the melanogenesis against α-melanocyte stimulating hormone (α-MSH)-activated B16 melanoma cells.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kwon Ki Bang, Cheong-Yong Yun, Chul Lee, Qinghao Jin, Jin Woo Lee, Sang-Hun Jung, Dongho Lee, Mi Kyeong Lee, Jin Tae Hong, Youngsoo Kim, Bang Yeon Hwang,