| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1369365 | Bioorganic & Medicinal Chemistry Letters | 2013 | 4 Pages |
Abstract
A total of 29 novel sulfenamide compounds were synthesized, spectroscopically characterized and evaluated in vitro for antimicrobial activity against various infectious pathogens. Compounds 1b and 2c exhibited potent inhibition against clinical Methicillin-resistant Staphylococcus aureus (MRSA) strains with minimum inhibitory concentration (MIC) values of 1.56 μg/mL.
Graphical abstractTwenty nine novel sulfenamide compounds were synthesized and their antimicrobial activities were evaluated. Compounds 1b and 2c exhibited strong anti-MRSA activity.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jian-Li Shang, Hui Guo, Zai-Shun Li, Biao Ren, Zheng-Ming Li, Huan-qin Dai, Li-Xin Zhang, Jian-Guo Wang,