| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1369387 | Bioorganic & Medicinal Chemistry Letters | 2013 | 7 Pages |
Abstract
Several non-benzimidazole containing inhibitors of respiratory syncytial virus are described. Core template modification, analysis of antiviral activity, physicochemistry and optimisation of properties led to the thiazole-imidazole 13, that showed a good potency and pharmacokinetic profile in the rat.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
David C. Pryde, Thien-Duc Tran, Iain Gardner, Helen Bright, Paul Stupple, Sebastien Galan, Liam Alsop, Lesa Watson, Donald S. Middleton, Satish Dayal, Michelle Platts, Edward J. Murray, Tanya Parkinson, Robert Webster,