Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1369503 | Bioorganic & Medicinal Chemistry Letters | 2016 | 4 Pages |
Abstract
To study the molecular action of ischemic Fas-mediated cell death inhibitor, we prepared fluorescent-tagged and biotin-tagged probes of the potent inhibitor, KR-33494, of ischemic cell death. We used the molecular modeling technique to find the proper position for attaching those probes with minimum interference in the binding process of probes with Fas-mediated cell death target, FAF1.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sung-eun Yoo, Changsun Yu, SeoHee Jung, Eunhee Kim, Nam Sook Kang,