| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1369518 | Bioorganic & Medicinal Chemistry Letters | 2016 | 4 Pages |
Abstract
A series of pyridoxine hydroxamic acid analog bearing a 5-aryl-spacers were synthesized. Evaluation of these novel HIV integrase complex inhibitors revealed compounds with high potency against wild-type HIV virus.
Graphical abstractA series of pyridoxine hydroxamic acid derivatives were prepared and evaluated as inhibitors of HIV integrase complex and wild type virus.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Brent R. Stranix, Jinzi J. Wu, Guy Milot, Françis Beaulieu, Jean-Emanuel Bouchard, Kristine Gouveia, André Forte, Seema Garde, Zhigang Wang, Jean-François Mouscadet, Olivier Delelis, Yong Xiao,