| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1369662 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
In this letter, we describe the first synthesis of two recently isolated flavones 5-carbomethoxymethyl-7-hydroxy-2-pentylchromone (3a), 5-carboethoxymethyl-4′,7-dihydroxyflavone (3b) and their derivatives (3c–t), evaluated for their antimicrobial, antioxidant and anticancer activities. Most of the synthesized compounds exhibited antimicrobial activity against the tested microbial strains and some of these compounds were found to be more potent as compared to the standard drugs like neomycin and luteolin. Interestingly, some of these synthesized compounds also showed moderate antioxidant property.
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Related Topics
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Chemistry
Organic Chemistry
Authors
Ahmed Kamal, J.N.S.R.C. Murty, A. Viswanath, P. Sujitha, C. Ganesh Kumar,