Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1369996 | Bioorganic & Medicinal Chemistry Letters | 2016 | 4 Pages |
Abstract
Sodium azide is toxic and widely used in agricultural, commercial products, and research laboratories. Thus it is of a significant environmental concern and there is a need for the development of a rapid detection method. A fluorogenic dibenzylcyclooctyne derivative (Fl-DIBO) is herein described as a fluorescent probe for the rapid detection of inorganic azide via Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC). Fl-DIBO was found to be highly selective toward NaN3 in comparison to other common anions with good sensitivity and detection limit of 10 μM.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ke Wang, Frédéric Friscourt, Chaofeng Dai, Lifang Wang, Yueqin Zheng, Geert-Jan Boons, Siming Wang, Binghe Wang,