| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1370081 | Bioorganic & Medicinal Chemistry Letters | 2016 | 4 Pages |
Abstract
A series of twenty resveratrol analogues was synthesized and tested on TRPA1 and TRPV1 channels. None was able to significantly modulate TRPV1 channels. Conversely, most of them exhibited remarkably higher TRPA1 modulating activity than resveratrol. Optimal potency was observed with ortho monoxygenated stilbenes 6 and 17.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Marianna Nalli, Giorgio Ortar, Aniello Schiano Moriello, Enrico Morera, Vincenzo Di Marzo, Luciano De Petrocellis,