Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1370091 | Bioorganic & Medicinal Chemistry Letters | 2016 | 5 Pages |
Abstract
The synthesis of curcumin–cyclodextrin/cellulose nanocrystals (CNCx) nano complexes was performed. CNCx were functionalized by ionic association with cationic β-cyclodextrin (CD) and CD/CNCx complexes were used to encapsulate curcumin. Preliminary in vitro results showed that the resulting curcumin–CD/CNCx complexes exerted antiproliferative effect on colorectal and prostatic cancer cell lines, with IC50s lower than that of curcumin alone.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gautier M.A. Ndong Ntoutoume, Robert Granet, Jean Pierre Mbakidi, Frédérique Brégier, David Y. Léger, Chloë Fidanzi-Dugas, Vincent Lequart, Nicolas Joly, Bertrand Liagre, Vincent Chaleix, Vincent Sol,