Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1370245 | Bioorganic & Medicinal Chemistry Letters | 2011 | 7 Pages |
Abstract
Thirty-one N4-mono alkyl derivatives of novel glycopeptide LYV07ww01 were synthesized by the reductive alkylation and their in vitro antibacterial activity was tested. The benzyl derivatives showed potent activity, especially against vancomycin-resistant enterococci and penicillin-resistant Streptococcus pneumoniae.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chang Shao, Weicheng Zhou, Shunli Zhang, Wei Wei, Lingao Ruan, Yiping Jin, Xinqiang Sun, Yanqin Huang,