Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1370269 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
Novel, highly potent small molecule HCV entry inhibitors are reported. The SAR exploration of a hit molecule identified from screening of a compound library led to the identification of highly potent compounds with IC50 values of <5Â nM in the tissue culture HCV infectious assay.
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Authors
Gopi Kumar Mittapalli, Andrew Jackson, Fang Zhao, Haekyung Lee, Stephine Chow, Jeffrey McKelvy, Flossie Wong-Staal, James E. Macdonald,