| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1370439 | Bioorganic & Medicinal Chemistry Letters | 2011 | 5 Pages |
Abstract
A series of pyrazole inhibitors of the human FPR1 receptor have been identified from high throughput screening. The compounds demonstrate potent inhibition in human neutrophils and attractive physicochemical and in vitro DMPK profiles to be of further interest.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Andrew D. Morley, Andrew Cook, Sarah King, Bryan Roberts, Sarah Lever, Richard Weaver, Cathy MacDonald, John Unitt, Malbinder Fagura, Tim Phillips, Richard Lewis, Mark Wenlock,