| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1370461 | Bioorganic & Medicinal Chemistry Letters | 2011 | 6 Pages |
Abstract
Pharmacophoric comparison between papaverine and tofisopam led to identify three new series of micro- to sub-micromolar inhibitors of phosphodiesterase-4, including 7,8-dialkoxy-2,3-benzodiazepin-4-one derivatives, 7,8-dialkoxy-1,4-benzodiazepin-2-one derivatives, and dialkoxybenzophenone derivatives.
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Related Topics
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Authors
Frédéric J.J. Bihel, Hélène Justiniano, Martine Schmitt, Malik Hellal, Mohamed A. Ibrahim, Claire Lugnier, Jean-Jacques Bourguignon,