Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1370524 | Bioorganic & Medicinal Chemistry Letters | 2015 | 4 Pages |
Abstract
New Salinomycin (SAL) bioconjugates with amino acid methyl esters were obtained and their antiproliferative activity against cancer cell lines including drug-resistant ones was studied. New compounds exhibit antiproliferative activity towards leukemia and doxorubicin-resistant colon adenocarcinoma cell line and are more effective and less toxic than the commonly currently used anticancer drugs.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Michał Antoszczak, Maria Sobusiak, Ewa Maj, Joanna Wietrzyk, Adam Huczyński,