Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1370583 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
Two new flavans (1, 2) and a new flavanone (3), together with three known compounds (4–6), were isolated from the roots of Iris tenuifolia. Their structures were elucidated by means of spectroscopic methods including 1D and 2D NMR techniques and mass spectrometry. Compounds 1, 4, and 6 were further confirmed by single-crystal X-ray diffraction analysis. Biological evaluation showed that compounds 1 and 4 were positive in inhibiting β-amyloid (Aβ) aggregation and promoting neural stem cells (NSCs) proliferation, respectively.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yan-Mei Cui, Hui Wang, Quan-Ru Liu, Mei Han, Yang Lu, Chang-Qi Zhao,