| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1370590 | Bioorganic & Medicinal Chemistry Letters | 2011 | 6 Pages |
Abstract
Five new isoprenylated flavonoids, notabilisins A–E (1–5), and two known Diels–Alder adducts (6 and 7), were isolated from the twigs of Morus notabilis. Compounds 4 and 5 possess two novel pyran rings, which may be biogenetically derived from 3. Compounds 1 and 3 significantly promoted adipogenesis, characterized by increased lipid droplet and triglyceride content in 3T3L1 cells, and induced up-regulation of the expression of adipocyte-specific genes, aP2 and GLUT4.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xiao Hu, Jun Ji, Meng Wang, Jin-Wei Wu, Qin-Shi Zhao, He-Yao Wang, Ai-Jun Hou,