| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1370599 | Bioorganic & Medicinal Chemistry Letters | 2011 | 5 Pages |
Abstract
A series of synthesized novel biscoumarin–chalcone hybrids were evaluated for their anti-inflammatory and antioxidant activity. The tested compounds significantly inhibit the carrageenin induced paw oedema in albino rats and also exhibit important scavenging activities. These compounds thus constitute an interesting template for the design of new therapeutic tools against inflammation.
Graphical abstractSynthesis and anti-inflammatory activity of novel biscoumarin–chalcone hybrids are reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Koneni V. Sashidhara, Manoj Kumar, Ram K. Modukuri, Ravi Sonkar, Gitika Bhatia, A.K. Khanna, Shivika Rai, Rakesh Shukla,