| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1370643 | Bioorganic & Medicinal Chemistry Letters | 2011 | 7 Pages |
Abstract
A novel series of 4-azetidinyl-1-aryl-cyclohexanes containing indazole or benzoisoxazole moiety have been identified as potent CCR2 antagonists with high selectivity versus hERG.
Graphical abstractA novel series of 4-azetidinyl-1-aryl-cyclohexanes containing indazole or benzoisoxazole moiety have been identified as potent CCR2 antagonists with high selectivity versus hERG.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xuqing Zhang, Heather Hufnagel, Cuifen Hou, Evan Opas, Sandra McKenney, Carl Crysler, John O’Neill, Dana Johnson, Zhihua Sui,