| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1370685 | Bioorganic & Medicinal Chemistry Letters | 2015 | 13 Pages |
Abstract
Specific neurons in the lateral hypothalamus produce the orexin neuropeptides (orexin-A and orexin-B). The orexin-peptides are transported to areas of the brain regulating sleep-wake cycles, controlling food intake or modulating emotional states such as panic or anxiety. The orexin system, consisting of the two orexin-neuropeptides and two G-protein-coupled receptors (the orexin-1 and the orexin-2 receptor) is as well involved in reward and addictive behaviors. The review reflects on the most recent activities in the field of orexin research.
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Related Topics
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Chemistry
Organic Chemistry
Authors
Christoph Boss, Catherine Roch,