Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1370746 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Matrix metalloproteinases (MMPs) are overexpressed in various pathological conditions, including cancers. Although these isozymes have similar active sites, the patterns of exposed amino acids on their surfaces are different. Herein, we report the synthesis and molecular interactions of two water soluble, fluorescent polymers which demonstrate selective interactions with MMP-9 compared to MMP-7 and -10.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Rinku Dutta, Michael D. Scott, Manas K. Haldar, Bratati Ganguly, D.K. Srivastava, Daniel L. Friesner, Sanku Mallik,