| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1370799 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
Novel types of PKCα activators based on isobenzofuranone bearing a myo-inositol moiety were designed and synthesized. The derivatives with bulky substituents on the myo-inositol moiety significantly activated PKCα, but their binding sites were not the same as that of phorbol ester.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Go Hirai, Megumi Ohkubo, Yuki Tamura, Mikiko Sodeoka,