Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1370996 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
Macrocyclic chelators have been extensively used for complexation of metal ions. A widely used chelator, DOTA, has been explored as a molecular platform to assemble multiple bioactive peptides in this paper. The multivalent DOTA-peptide bioconjugates demonstrate promising tumor targeting ability.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xiaofen Zhang, Hongguang Liu, Zheng Miao, Richard Kimura, Feiyue Fan, Zhen Cheng,