| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1371003 | Bioorganic & Medicinal Chemistry Letters | 2011 | 5 Pages |
Abstract
Learnings from previous Roche p38-selective inhibitors were applied to a new fragment hit, which was optimized to a potent, exquisitely selective preclinical lead with a good pharmacokinetic profile.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
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Authors
Michael Soth, Sarah Abbot, Allassan Abubakari, Nidhi Arora, Humberto Arzeno, Roland Billedeau, Nolan Dewdney, Kieran Durkin, Sandra Frauchiger, Manjiri Ghate, David M. Goldstein, Ronald J. Hill, Andreas Kuglstatter, Fujun Li, Brad Loe, Kristen McCaleb,